A novel 1,l0-bis(2-phenylethan-1-ol)ferrocene (1,10-BEOF) is synthesized and used for the modification of
a carbon paste electrode in the presence of ZnO nanoparticles (ZnO/NPs) as a sensor in captopril (CAP)
drug determination. The new sensor shows excellent electrocatalytic activity for the electro-oxidation of
CAP and reduction of charge transfer resistance. The square wave voltammogram (SWV) currents
increase linearly with CAP concentration in the oxidation range of 0.09–450.0 mmol L1 and the
detection limit for CAP was 0.05 mmol L1. The relative standard deviation for five successive assays of
10.0 mmol L1 CAP was 1.9%. For further investigation, the novel sensor was employed for the
determination of CAP in drug and urine samples.
کلید واژگان :
zinc oxide nanoparticles and a new ferrocene-derivative
