Investigate prevalence of cardiac complications in patients with thalassemia major

Introduction: Beta thalassemia major is a genetic disorder of hemoglobin beta the chain production and lifespan of red blood cells is leading to a sharp decline.one of the most important complications in patients with iron deposition in heart tissue that causes fibrosis and impaired heart's workload. Heart disease is a major cause of mortality in these patients. Heart disorder is a major cause of mortality in these patients. Since the Iran is located in the thalassemia belt where there is a need for research in the field cardiac complications. Methods: This review article is to review and summarize numerous articles of databases and scientific sites Google scholar, magiran, Sid, PubMed Embase and iranmedex by keyword cardiac complications, prevalence, thalassemia during 2000 and 2016 was. Results: The results showed that people with major thalassemia who were ages one to 25 years, Between 7 - 11.4 have been diagnosed with cardiac complications.prevalence cardiac complications in patients with no statistically significant gender but age been achieved meaningful. No significant relationship between the prevalence cardiac complications ferritin levels were not But it has been proven that lack of control and lack desferal right reasonable ferritin or low and irregular that it will help increase your Iron overload due to frequent blood transfusions are effective Which leads to increased cardiac complications. Conclusion: In patients should be taken echocardiography in terms of heart problems. The ferritin levels checked regularly, at least every six months and should receive Desferal appropriate level of ferritin.

cardiac complications, prevalence, thalassemia major