Evaluation of anticancer effect of saffron in native dogs with liver metastasis in Tehran province

Introduction Saffron is a perennial, stemless herb belonging to Iridaceae family. It is cultivated in various countries such as Iran, Greece, Spain, China and Turkey. 20 mg Saffron tablets are safe to use in human and animals on applied studies. Cancer, an important health problem, is a major cause of mortality around the world. Anti-cancer effect of Saffron in hepatic metastasis have been investigated in human but not in dogs, so we aimed to evaluation this effect in dogs. Synthesis For this reason, 12 mixed breed dogs from both sexes that had hepatic metastasis were randomly divided in to two 6 number groups. In group I (control), after confirmation their liver problem by taking MRI from their liver, they have been received drug as chemotherapy, alone. Second group (test), have been received 20 mg Saffron tablet/daily in addition to the chemotherapy for a month. Results and Discussions After 30 treatment day, test group were health, totally but 4 dog of the control group were been health. In result, Saffron can be used to as anticancer herbal drug in treatment of hepatic metastasis in dogs as humans for its crocin substance as a safe drug. It must apply more studies about this result in other dogs, too.

anticancer effect liver metastasis