Three-component reaction of 1-(6-hydroxy-2-isopropenyl-1-benzofuran-yl)-1-ethanone, dialkyl acetylenedicarboxylates
and
isocyanides
in
water
was
described
as
efficient
and
green
synthetic
procedure
for
preparation
of
9Hfuro[2,3-f]chromene-8,9-dicarboxylates
in
excellent
yield.
In
these
reactions,
1-(6-hydroxy-2-isopropenyl-1-benzofuranyl)-1-ethanone
was
extracted
from
rhizomes
of
Petasites
hybridus
from
northern
Iran.
The
structure
of
this
compound
was
determined
by
1
H,
13
C-NMR and IR spectroscopy and confirmed by X-ray diffraction analysis. This procedure provides
rapid access to novel and diversely substituted 9H-furo[2,3-f]chromene-8,9-dicarboxylate derivatives.
