چکیده :

tIntroduction: Occurrence of leishmaniasis is affected by various biological and environmental factors.Kohgiluye and Boyerahmad (K–B) province is an emerging focus of cutaneous leishmaniasis (CL) inSouthwest Iran.Subjects and methods: To elucidate some angles of occurrence of CL in this province, climatic and environ-mental factors and close proximity to livestock were studied by univariate and two multivariate logisticregression models. The dwelling addresses of 275 CL patients were obtained from Health Centers recordsfor a 5 years period. The effect of mean annual temperature, minimum mean annual temperature, maxi-mum mean annual temperature, mean annual rainfall, slope, elevation, land covers and close proximityto cattle and sheep/goat sheds on the occurrence of CL were analysed using geographical informationsystems (GIS) approach.Results: CL occurred in all counties with the most cases in Northwest, West and South semi-arid and warmregions. Land cover, slope, elevation and close proximity to cattle sheds, were the most effective factors.Urban, dry farm and thin rangeland were found as the most important land covers. Slope and elevationdecreased the probability of disease. Close proximity to cattle sheds notably increased the chance of CL.The importance of other factors such as rainfall, temperature and close proximity to sheep/goat shedsonly were shown when their effects were evaluated independently from other factors. So regions withurban, dry farm and thin rangeland covers with lower slope and altitude where in close proximity ofcattle sheds seems to be potentially most high risk areas.Conclusion: Distribution of CL cases is influenced by combination of environmental, ecological factors andclose proximity to livestock sheds but control programs should be focused on cities and villages in theabove-mentioned most high risk regions.

کلید واژگان :

Cutaneous leishmaniasisGISLand coverSlopeElevationa



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