Fe3O4@SiO2/Schiff base complex of Cu(II) efficiently catalyzes condensation reaction of isatoic anhydride, aldehydes, and primary amines or ammonium salts to afford the corresponding 2,3-dihydroquinazolin-4(1H)-one derivatives in ethanol under reflux conditions. This method gives notable advantages such as easy work-up, high yields, short reaction times. Also, the aforementioned nanocatalyst can be easily recovered by a magnetic field and reused for subsequent reactions for at least 8 times without noticeable deterioration in catalytic activity.
کلید واژگان :
2, 3-Dihydroquinazolin-4(1H)-ones, Isatoic anhydride, One-pot synthesis, Magnetic nanocatalyst, Recyclable catalyst
