The frequency of candiduria in hospitalized patients with depressive syndrome

Background and objectives: The presence of different species of Candida in urinary system is considered as candiduria. Depressive syndrome is an unpleasant and debilitating disease that causes several depressive disorders in patient behavior. Depressive syndrome increased appetite, weight gain and constant sleeping with the dominant group "atypical" fit. The aim of present study was to identify and compare candiduria in patients with depressive syndrome with healthy individuals. Materials and Methods: In this study on 131 patients admitted to Salamat and Boustan hospitals were sampled. In addition 105 healthy individuals were also sampled as control. Urine samples were collected in sterile urine bottles and transferred medical mycology laboratory, department of medical mycology, Ahvaz. 50μl of uncentrifuged urine samples was inoculated on CHROMagar Candida and incubated at 37°C for one week. All yielded yeasts were colony counted and identified based on morphology on CHROMagar Candida, production of germ tubes on serum, and formation chlamydoconidia on cornmeal agar with 1% Tween 80. Results: Our study shows that 2.3% and 13.3% of patients and control were respectively positive for candiduria. In the present study, 14 (13.3%) urine samples from control group was positive for Candida species, whereas only 2.3% of cases were positive. In both groups, females were affected by yeasts. The most common isolated yeasts were C. albicans and C. glabrata. Conclusion: Candiduria was most prevalent in control group than patients, treated for depressive syndrome by several drugs.

Candiduria, Candida albicans, Depressive syndrome