An efficient and general method has been developed for synthesis of 1- and 5-substituted 1H-tetrazoles
from nitriles and amines using magnetite nanoparticles immobilized Salen Cu(II) as an efficient and
recyclable catalyst. The structural and magnetic properties of functionalized magnetic silica are identified
by transmission electron microscopy (TEM), scanning electron microscopy (SEM) and vibrating sample
magnetometer (VSM) instruments. NMR, FT-IR, elemental analysis and XRD were also used for identification
of these structures.
Nanocatalyst can be easily recovered by a magnetic field and reused for subsequent reactions for at
least 7 times with less deterioration in catalytic activity.
