A facile synthesis of α,α′-bis(substituted benzylidene) cycloalkanones catalyzed by p-TSA under solvent-free conditions

Various 2,6-dibenzylidene cycloalkanones were readily prepared in a few minutes with good yields by simply mixing aromatic aldehydes with cycloalkanones in the presence of catalytic amounts of p-toluenesulfonic acid as a solid heterogeneous catalyst under solvent-free condition.

a,a? -bis(substituted benzylidene) cycloalkanones; p-toluenesulfonic acid; cross-aldol condensation; aldehydes; green chemistry