In this protocol, Ag supported on the hydroxyapatite-core-shell magnetic γ-Fe2O3
nanoparticles (γ-Fe2O3@HAp-Ag NPs) as a novel, efficient, and magnetically recyclable
catalyst is synthesized, and characterized by transmission electron microscopy (TEM),
scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray
diffraction (XRD), and vibrating sample magnetometry (VSM). The use of the catalyst is
described in the synthesis of coumarin derivatives by the Pechmann condensation of various
phenols with β-ketoesters under solvent- and halogen-free conditions at 80 ºC. This novel and
inexpensive method offers advantages, such as recyclability simple experimental protocol,
short reaction time, minimal work-up procedure, and excellent yields of products, together
with desirable, eco-friendly, green aspects by avoiding toxic elements and solvents, and ease of
recovery from the reaction mixture using an external magnet.
کلید واژگان :
γ-Fe2O3 nanocatalyst Heterogeneous catalyst Pechman condensation Ag supported
