Phytochemical investigation of Beilschmiedia alloiophylla has resulted in the isolation of one
new alkaloid, 2-hydroxy-9-methoxyaporphine (1), and ten known natural products, laurotetanine
(2), liriodenine (3), boldine (4), secoboldine (5), isoboldine (6), asimilobine (7),
oreobeiline (8), 6-epioreobeiline (9), β-amyrone (10), and (S)-3-methoxynordomesticine
(11). Chemical studies on the bark of B. kunstleri afforded compounds 2 and 4 along with
one bisbenzylisoquinoline alkaloid, N-dimethylphyllocryptine (12). Structures of compounds
1–12 were elucidated on the basis of spectroscopic methods. All of these isolates
were evaluated for their anti-acetylcholinesterase (AChE), anti-α-glucosidase, antileishmanial
and anti-fungal activities. Compounds 1–12 exhibited strong to moderate bioactivities
in aforementioned bioassays.
