Effect Halothane-Induced Anesthesia on Plasma Cortisol in Celiotomy in Pigeon

Abstract: Blood biochemical factors are changed by anesthesia in birds. Cortisol is one of these factors which related to inflammation and pain at surgery or post-operation. In present study, we evaluated effect of halothaneinduced anesthesia on plasma level of cortisol in pigeon. Ten domestic pigeons were used. The weight of birds was about 300 g. After 3 to 4 h food restriction, anesthesia was induced by halothane for celiotomy within 20 min. Anesthesia was induced by halothane at 2.5% with oxygen gas and it continued by 1.5% halothane. Blood sample was collected before, during and after surgery from pigeons and plasma level of cortisol was measured by commercial kit. Anesthesia induction and maintenance with halothane provided suitable anesthesia during celiotomy in pigeon. Plasma level of cortisol was significantly decreased after anesthesia. The mean of cortisol was 2.02 ng/mL before anesthesia and reached to 1.75 and 1.59 ng/mL in during and after anesthesia respectively. This change significantly differed with comparison to before surgery. But the mean of cortisol was not different significantly between duration of surgery and post operation. Halothane can decrease level of cortisol during anesthesia and so it decreases anti-inflammatory and analgesic effect of cortisol and also side effect of corticostroids.

Anesthesia, cortisol, halothane, pigeon