Periodontal diseases (PDs) include a group of inflammatory diseases characterized by periodontium hard and soft tissues destruction leading to host immune response activation. It has been suggested that bacterial infection-induced direct tissue damages along with indirect effects of host immune responses play roles in pathogenesis of PDs. Increasing numbers of reports have provided strong evidence that there is a potential association between maternal PDs and delivery of preterm low birth weight infants. Moreover, having PDs during pregnancy has been linked with an increased risk for preeclampsia. Previous reports have also exhibited that PDs are associated with significant higher percentage of endometriosis and maternal PDs can affect the effectiveness of infertility therapies and in vitro fertilization success. Increased levels of inflammatory mediators including PGE2 and TNF due to lipopolysaccharides production by periodontopathic bacteria have been attributed to adverse pregnancy outcomes. Since PDs may increase the risk of perinatal mortality and developmental disorders as well as infertility treatments failure, oral health promotions through well-organized strategies should be prioritized particularly in mothers-to-be.
کلید واژگان :periodontium, endometriosis, pregnancy, fertilization
ارزش ریالی : 300000 ریال
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