Evaluation the Rate of Cancer Risk in Patients with Diabetes: A Systematic Review

Introduction: Patients with diabetes increase the risk of cancer by 20 to 25 percent compared to those without diabetes. Cancer is one of the major causes of death in the world and mortality rates are higher in developed countries. Diabetes seems to increase the risk of developing various types of cancer. Therefore, this systematic review was conducted to determine the rate of cancer risk in Patients with Diabetes. Materials and Methods: This study is a systematic overview That using articles published in the last 30 years about the risk of cancer in diabetic patients. Searching for articles in search engines, authoritative sites and databases SID, Magiran, Google Scholar, Research gate, Science direct, Google Scholar, PubMed, Springer in Persian and English. In the first stage, 42 articles were found. Of these, 10 related articles that have been published over the past 30 years have been reviewed. Results: In several studies, there was a positive relationship between cancer and diabetes, one study, conducted by Manami Inoue et al., Entitled "Diabetes and the risk of cancer”, In men, the risk of overall cancer increased by 27% in those with a history of diabetes. In this study, we also saw an increased risk of colon cancer and gastric cancer with borderline significance. In women, the incidence of cancer was significantly increased at the borderline, while the incidence of gastric cancer and liver cancer was statistically significant and the incidence of ovarian cancer was observed at the border. Conclusion: Different studies have shown that there was a direct and significant correlation between the risk of various types of cancer in diabetic patients. Due to the high prevalence of diabetes in the world and the risk of cancer, it is better be done to plan the Ministry of Health in Iran and the World Health Organization to reduce diabetes and cancer.

Cancer, Diabetes, Risk Factor, Diabetic Patients