Pathogenic role of H. pylori in the incidence of coronary artery disease

Objectives: Helicobacter pylori is a gram negative and microaerophilic that more than half of the world population are infected. The findings show that these bacteria as a risk factor for coronary artery disease. There was a high complication of chronic obstructive pulmonary disease in patients with CAD. The aim of this study was to investigate the pathogenic role of H. pylori in the incidence of coronary artery disease. Material and method: This study is a review and the findings of its obtained of the collected findings by researchers who have explored in this field. Results: The findings Rostamzadeh and colleagues showed that in 85% of patients were observed relationship between HP and CAD. Rogha et al found that patients infected with H. pylori are three times more at risk of CAD. The trial Vc~ev et al, findings showed a higher seroprevalence of HP in patients with CAD compared to controls (78.8% versus 8.35%). Mirzababaei and his colleagues study on 876 people, 63% of coronary artery disease and 33% of controls had H. pylori infection. In study Kowalski et al, was seen the prevalence of HP in patients with CAD more than healthy group with of similar age and gender. The findings of Vafaeimanesh and his colleagues showed that H. pylori is more prevalent among patients with CAD. Huang et al found that the severity of coronary atherosclerosis increased in the group with H. pylori. Conclusion: H. pylori infection is one of the probable risk factors for coronary artery disease.

Pathogenesis, Helicobacter pylori, coronary artery disease