EVALUATION OF ANTIBACTERIAL ACTIVITY OF ESSENTIAL OIL OF ZIZIPHORA CLINOPODIOIDES AND ACHILLEA WILHELMSII ON ANTIBIOTIC- RESISTANT STRAINS OF STAPHYLOCOCCUS AUREUS

Background and Aim:Infections caused by antibiotic-resistant strains of Staphylococcus aureus are mainly hospital-based prevalence is increasing in many countries; Hence efforts taken to find new compounds as an alternative to antibiotics. This study is done to evaluate the antimicrobial effects of Essential Oil of Ziziphora clinopodioides and Achillea wilhelmsii on against resistant clinical strains of Staphylococcus aureus. Methods:After collecting plants and validate its scientific name by botanists of Agricultural Organization and after drying in shade, Essential Oil of Ziziphora clinopodioides and Achillea wilhelmsii, extracted with steam distillation method by Clevenger and antimicrobial effects of Essential Oil by well diffusion on above mentioned bacteria were interpreted. Amount of Essential Oil were injected to gas chromatography linked to mass spectrometry (GC / Ms), and the amount and type compounds of the Essential Oils were identified. Results:The results showed that the extracted essence Essential Oil from the Ziziphora clinopodioides and Achillea wilhelmsii has bactericidal effect. In the obtained results by GC/Ms chromatography, in Ziziphora clinopodioides and Achillea wilhelmsii Essential Oils, 22 and 18 compounds, were identified respectively. Conclusion:The results of this study show that can be taken Ziziphora clinopodioides and Achillea wilhelmsii in herbals groups with antibacterial properties and after evaluating their effects in vivo condition and to identify the active ingredients, as an alternative to synthetic drugs that commonly used to treat infections are used

Antibacterial effects, Essential Oil , Staphylococcus aureus