comparison between Trachyspermum ammi, thyme and cotrimoxazole in the treatment of diarrhea caused by E. coli in rabbits

Introduction Rabbit-origin enteropathogenic E. coli (EPEC) causes substantial diarrhea-associated morbidity and has zoonotic potential. We decided to investigate the therapeutic effects of C. copticum as one of the medicinal plants of Tehran with thyme as herbal medicine and cotromoxazole as E. coli antimicrobial agent in the treatment of rabbits with gastrointestinal infection after clinical examination and culture of the shed, E. coli were isolated, too. We can find Trachyspermum ammi in Iran, in Sistan-Baluchistan, Azerbaijan, Isfahan, Khuzestan, Fars, Kerman and Khorasan. Thyme is pretty in all of parts of Iran, too. Synthesis 15 number of two month pet rabbits with diarrhea in Tehran were randomly selected that was referred to us as pet clinic and then detected and confirmed the presence of E. coli bacteria digestive problems due to high load randomly divided into 3 groups 5. The first group twice daily for 1 week once every 12 hours of liquid extracts (tinctures) C. copticum (Because of the bitter taste of this plant) 3 ml each time orally. The second group received twice daily orally every 12 hours, two drops of thyme oil were fed to a control group and the third group was also, every 12 hours 30 mg tablets were fed cotrimoxazole.  Results and Discussions After a week of prescribing these drugs results were as follows: C. copticum and thyme recipient groups like the group receiving oral antibiotic tablets of cotrimoxazole as your digestive quite recovered his health and appetite also returned to normal. At the end of the three groups of gastric fluid culture results were negative for E. coli. Because of the many advantages of traditional medicine and herbs and Its low disadvantages compared to chemical drugs and These drugs are easily accessible in nature, especially plants C. copticum in Tehran specially on rabbits and also, these drugs lower price than similar chemical it’s better to replace these drugs with recent like chemical drugs by Pharmaceutical companies after more Supplementary researches. It should be noted that the active ingredient in disinfectants against E. coli both in Thyme and C. copticum is thymol and carvacrol. It must be noted that we earlier found the same findings in using these herbal drugs on dogs in Khuzestan province, too.

E. coli