Background: This study aimed to determine multiple re- sistance in Enterococcus faecalis strains isolated from clinical samples in hospitals and health centers of Marand and Ta- briz City. Methods: 200 Enterococcus samples were collected from hospitals and health centers of Marand and Tabriz. Enterococ- cus species were identified by common standard phenotype and PCR methods. Susceptibility test to antibiotics was per- formed based on standard diffusion method CLSI. Drug resistance (MIC) was performed by E-test method on van- comycin-resistant samples. Results: Of 200 isolate samples, 100 Enterococcus faecalis sam- ples were identified. Susceptibility test results to antibiotics showed that Enterococcus faecalis had highest resistance to pen- iciline (83%), tetracycline (43%) and ciprofloxacin (41) and the highest susceptibility to linezolid (87%), Imipenem (85%) and Teicoplanin (70%). MIC for vancomycin-resistant samples was ranging 32 to 256 µg. Multiple drug phenotype (resistance to three or more than three antibiotic classes) was observed in 30 strains. Conclusion: The resistance to some antibiotics and high resistance to vancomycin are considered in Enterococcus faecalis strains as the selection of good treatment for infections by Enterococcus is reduced.
کلید واژگان :
Enterococcus faecalis, vancomycin-resistance Enter- ococcus, Multiple drug resistance
