The role of Chlamydophila pneumonia in patho-genesis of atherosclerosis is one of the most important discussions in coronary artery dis-eases. In this study, the relationship between C. pneumoniae seropositivity and atherosclerotic plaque was evaluated among two groups; one group with significant coronary stenosis and one group with normal coronary angiography. Serum C. pneumonia IgM and IgG was evaluated and compared in case and control groups. The IgM and IgG antibodies seropositivity rate were not statistically differ between case and control groups, although the incidence of positivity were more in case group. The results of our study did not show a correlation between C. pneumonia infection and atherosclerotic plaque or coronary artery stenosis neither in acute nor in chronic infection. More precise studies are needed to clarify the probable inflammatory cascade that starts with C. pneumonia infection and lead to development of atherosclerotic plaque.
