An efficient, green and environmentally procedure for the synthesis of spiro [chromeno[2, 3-c] pyrazole-4,3'-indoline]-diones derivatives has been developed by a one-pot three-component reaction of isatin derivatives, dimedone, ethyl acetoacetate and hydrazine hydrate in the presence of Fe3O4@SiO2-imid-PMAn magnetic nanocatalyst in aqueous ethanol under reflux conditions. Moreover, this catalyst could be recovered easily by an external magnetic field and reused six times without significant loss in activity.
کلید واژگان :
Multicomponent reactions; One-pot synthesis; Spirooxindoles; Nanostructures; Magnetic separation.
