The Valerian plant is known as a medicinal plant with sedative, anxiolytic, anti-inflammatory properties and somnifacient effect. Therefore studying cardiac effects of this plant can help to gain a better understanding of its pharmacodynamics effects in order to provide above properties. In this research 18 healthy female pet cats, 2 years old in the mean, were selected. Cardiac function indexes including the fractional shortening, ejection fraction and normal stroke volume were measured using echocardiography. Cats were fed by 500 mg/kg Valerian root extract and clinical signs like distraction and incoordination were observed after 15 minutes; the factors were measured. Results were analyzed by the statistical method of independent T-test. Obtained data was showed satisfactory results which are detailed described in the text below. The results showed that stroke volume index increased significantly while fractional shortening index decreased significantly. Also the ejection fraction index was not significant statistically. Therefore extract of the Valerian root decreases the sympathetic performance, effects on the heart indirectly, relaxes the myocardium in result of the decrease in the fractional shortening of the heart muscle and consequently increases the diastolic and systolic volume and increases the stroke volume of the blood accompanied by the decrease in the preload and after load.
کلید واژگان :Valerian root extract, echocardiography, Cat, cardiac function index, ejection fraction, stroke volume
ارزش ریالی : 600000 ریال
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