Marrubium vulgare (Family: Lamiaceae) was used traditionally in the treatment of dyspeptic complains, pulmonary
infections, cough, rheumatoid arthritis, night blindness, loss of appetite, as cholagogue, purgative, diuretic, bitter tonic,
carminative and appetizer. The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids,
terpenoids (diterpene), saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other
bioactive ingredients. The pharmacological investigations showed that the plant exerted anti-inflammatory,
antiedematogenic, analgesic, antioxidant, antimicrobial, antidiabetic, cardiovascular hypolipidemic, antispasmodic and
many other biological effects. This review discussed the bioactive contents and pharmacological activities of Marrubium
vulgare.
کلید واژگان :
Marrubium vulgare; metabolites; constituents; traditional uses; pharmacology; therapeutic; toxicity
