Evaluation of antibacterial activity of ethanolic extract of Malva Neglecta And Althaea Officinalis L. on Antibiotic-Resistant Strains of Escherichia coli

With the increasing awareness of the dangerous effects of synthetic antibiotics, Demand for natural herbal drugs and cheap and without side effects has increased. The present study aims to investigate antibacterial effects of ethanolic extract of Malva neglecta and Althaea officinalis L. on antibiotic-resistant strains of E. coli. After collecting herbs and approval of its scientific name by botanists of Iranian Agriculture Organization, the extract of Malva neglecta and Althaea officinalis L were prepared by vacuum distillation procedure. Then Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extracts was determined on E. coli. strains isolated from patients with broth micro dilution and Agar dilution method. Results showed that MIC and MBC of ethanolic extracts of Malva neglecta against E. coli.were 6.5 and 13 mg/ml and MIC and MBC of Althaea officinalis L. extract on E. coli.were 3.2 and 6.5 mg/ml. These results indicated that Malva neglecta and Althaea officinalis L., could be considered as a group of herbs with antibacterial properties. Thus, it can be used widely in traditional medicine in this regard

Antibacterial effects, Malva neglecta, extracts, Althaea officinalis E. coli.